6 month serologic response to the Pfizer-BioNTech COVID-19 vaccine among healthcare workers

Healthcare workers (HCWs) were among the first group of people vaccinated with the Pfizer-BioNTech Covid-19 vaccine (BNT162b2). Characterization of the kinetics of antibody response to vaccination is important to devise future vaccination strategies. To better characterize the antibody response to BNT162b2, we analyzed the kinetics of IgG and IgM antibody response to 5 different SARS-CoV-2 epitopes over a period of 6 months.

Cell Reports Methods, Rapid detection of an Ebola biomarker with optical microring resonators

Qavi et al. describe a method using microring resonator sensors to detect Ebola virus (EBOV) soluble glycoprotein (sGP) in serum. sGP is a promising biomarker for the prognosis of EBOV infection and, coupled with this rapid detection method, could lead to a faster diagnosis.

Highlights

• sGP is a unique diagnostic marker of Ebola virus infection
• Microring resonators can detect EBOV and SUDV sGP at low ng/mL concentrations
• Our sandwich immunoassay design enables the detection of antigens from serum
• Multiplex chip has flexible design, technical replicates, and integrated controls